Stereoselective synthesis of alpha-C-(alkynyl)-glycosides via ring-opening of alpha-1,2-anhydrosugars

被引：41

作者：

Leeuwenburgh, MA

Timmers, CM

vanderMarel, GA

vanBoom, JH

Mallet, JM

Sinay, PG

机构：

[1] LEIDEN UNIV,LEIDEN INST CHEM,NL-2300 RA LEIDEN,NETHERLANDS

[2] ECOLE NORMALE SUPER,DEPT CHIM,F-75231 PARIS 05,FRANCE

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 35期

关键词：

D O I：

10.1016/S0040-4039(97)01381-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ring-opening of an alpha-1,2-epoxide function in sugars with lithium alkynyl derivatives in the presence of zinc chloride proceeds with retention of configuration to afford alpha-C-(alkynyl)-glycosides in reasonable yields. (C) 1997 Elsevier Science Ltd.

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收藏

页码：6251 / 6254

页数：4

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