Tailoring Functional Interlayers in Organic Field-Effect Transistor Biosensors

被引:73
作者
Magliulo, Maria [1 ]
Manoli, Kyriaki [1 ]
Macchia, Eleonora [1 ,2 ]
Palazzo, Gerardo [1 ]
Torsi, Luisa [1 ]
机构
[1] Univ Bari Aldo Moro, I-470125 Bari, Italy
[2] Univ Bari A Moro, Dipartimento Interateneo Fis M Merlin, I-470125 Bari, Italy
关键词
THIN-FILM TRANSISTORS; SELF-ASSEMBLED MONOLAYERS; ELECTROCHEMICAL TRANSISTORS; DNA; ELECTRONICS; INTERFACE; PERFORMANCE; DIELECTRICS; PENTACENE; INTEGRATION;
D O I
10.1002/adma.201403477
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
This review aims to provide an update on the development involving dielectric/ organic semiconductor (OSC) interfaces for the realization of biofunctional organic field-effect transistors (OFETs). Specific focus is given on biointerfaces and recent technological approaches where biological materials serve as interlayers in back-gated OFETs for biosensing applications. Initially, to better understand the effects produced by the presence of biomolecules deposited at the dielectric/OSC interfacial region, the tuning of the dielectric surface properties by means of self-assembled monolayers is discussed. Afterward, emphasis is given to the modification of solid-state dielectric surfaces, in particular inorganic dielectrics, with biological molecules such as peptides and proteins. Special attention is paid on how the presence of an interlayer of biomolecules and bioreceptors underneath the OSC impacts on the charge transport and sensing performance of the device. Moreover, naturally occurring materials, such as carbohydrates and DNA, used directly as bulk gating materials in OFETs are reviewed. The role of metal contact/OSC interface in the overall performance of OFET-based sensors is also discussed.
引用
收藏
页码:7528 / 7551
页数:24
相关论文
共 98 条
[71]   Direct growth of aligned graphitic nanoribbons from a DNA template by chemical vapour deposition [J].
Sokolov, Anatoliy N. ;
Yap, Fung Ling ;
Liu, Nan ;
Kim, Kwanpyo ;
Ci, Lijie ;
Johnson, Olasupo B. ;
Wang, Huiliang ;
Vosgueritchian, Michael ;
Koh, Ai Leen ;
Chen, Jihua ;
Park, Jinseong ;
Bao, Zhenan .
NATURE COMMUNICATIONS, 2013, 4
[72]   Fabrication of low-cost electronic biosensors [J].
Sokolov, Anatoliy N. ;
Roberts, Mark E. ;
Bao, Zhenan .
MATERIALS TODAY, 2009, 12 (09) :12-20
[73]   Organic field-effect transistors and memory elements using deoxyribonucleic acid (DNA) gate dielectric [J].
Stadler, Philipp ;
Oppelt, Kerstin ;
Singh, Thokchom Birendra ;
Grote, James G. ;
Schwoediauer, Reinhard ;
Bauer, Siegfried ;
Piglmayer-Brezina, Heidi ;
Baeuerle, Dieter ;
Sariciftci, Niyazi Serdar .
ORGANIC ELECTRONICS, 2007, 8 (06) :648-654
[74]   DNA - a new material for photonics? [J].
Steckl, Andrew J. .
NATURE PHOTONICS, 2007, 1 (01) :3-5
[75]   Insulating behavior for DNA molecules between nanoelectrodes at the 100 nm length scale [J].
Storm, AJ ;
van Noort, J ;
de Vries, S ;
Dekker, C .
APPLIED PHYSICS LETTERS, 2001, 79 (23) :3881-3883
[76]   Dynamics of deoxyribonucleic acid solutions as studied by dielectric relaxation spectroscopy and dynamic mechanical spectroscopy [J].
Sun, MY ;
Pejanovic, S ;
Mijovic, J .
MACROMOLECULES, 2005, 38 (23) :9854-9864
[77]   Organic bioelectronics in nanomedicine [J].
Svennersten, Karl ;
Larsson, Karin C. ;
Berggren, Magnus ;
Richter-Dahlfors, Agneta .
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2011, 1810 (03) :276-285
[78]  
Sze S. M., 2006, Physics of semiconductor devices, V3rd, DOI DOI 10.1002/0470068329
[79]   Organic electrochemical transistors monitoring micelle formation [J].
Tarabella, Giuseppe ;
Nanda, Gaurav ;
Villani, Marco ;
Coppede, Nicola ;
Mosca, Roberto ;
Malliaras, George G. ;
Santato, Clara ;
Iannotta, Salvatore ;
Cicoira, Fabio .
CHEMICAL SCIENCE, 2012, 3 (12) :3432-3435
[80]   Cellulose-Based Ionogels for Paper Electronics [J].
Thiemann, Stefan ;
Sachnov, Swetlana J. ;
Pettersson, Fredrik ;
Bollstrom, Roger ;
Osterbacka, Ronald ;
Wasserscheid, Peter ;
Zaumseil, Jana .
ADVANCED FUNCTIONAL MATERIALS, 2014, 24 (05) :625-634