Proteomics in pancreatic disease

被引：15

作者：

Löhr, M ^{[1
]}

Faissner, R ^{[1
]}

机构：

[1] Heidelberg Univ, Med Fac Mannheim, Dept Med 2, Heidelberg, Germany

来源：

PANCREATOLOGY | 2004年 / 4卷 / 02期

关键词：

proteomics; proteome; pancreas; pancreatology; pancreatitis; pancreatic carcinoma; review;

D O I：

10.1159/000077212

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Proteomics represents a novel methodological approach to investigate the expression of all proteins by a cell or organism in its entireness, similar to global strategies for DNA (genomics) and RNA (transcriptomics). This review focuses on the history of protein analysis, which made up the golden age of pancreatic physiology, the current methodology for proteomics (2D gel electrophoresis, mass spectrometry) and the few published experiences with proteomics in the field of pancreatology until now. Finally, potential applications of proteomics for the pancreas, in concert with other techniques, are cited. Copyright (C) 2004 S. Karger AG, Basel and IAP.

引用

页码：67 / 75

页数：9

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