Timeline - Radiation oncology: a century of achievements

被引:420
作者
Bernier, J [1 ]
Hall, EJ
Giaccia, A
机构
[1] Oncol Inst So Switzerland, Dept Radiooncol, CH-6504 Bellinzona, Switzerland
[2] Columbia Univ, Ctr Radiol Res, New York, NY 10032 USA
[3] Stanford Univ Sch, Dept Radiat Oncol, Div Radiat & Canc Biol, Stanford, CA 94305 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1038/nrc1451
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Over the twentieth century the discipline of radiation oncology has developed from an experimental application of X-rays to a highly sophisticated treatment of cancer. Experts from many disciplines-chiefly clinicians, physicists and biologists-have contributed to these advances. Whereas the emphasis in the past was on refining techniques to ensure the accurate delivery of radiation, the future of radiation oncology lies in exploiting the genetics or the microenvironment of the tumour to turn cancer from an acute disease to a chronic disease that can be treated effectively with radiation.
引用
收藏
页码:737 / U15
页数:12
相关论文
共 94 条
[21]  
ELLIS F, 1965, CURR TOP RADIAT RES, V4, P357
[22]  
Failla G, 1928, AM J ROENTGENOL RADI, V20, P128
[23]   An objective method for the administration of X-rays [J].
Failla, G .
ACTA RADIOLOGICA, 1925, 4 (02) :85-128
[24]  
Fletcher G H, 1979, Int Adv Surg Oncol, V2, P55
[25]  
Folkman J., 2001, HARRISONS PRINCIPLES, V15th ed., P517
[26]  
Freund L, 1903, GRUNDRISS GESAMTEN R
[27]   A TRAVELLING-WAVE LINEAR ACCELERATOR FOR 4-MEV ELECTRONS [J].
FRY, DW ;
HARVIE, RBRS ;
MULLETT, LB ;
WALKINSHAW, W .
NATURE, 1948, 162 (4126) :859-861
[28]   TRAVELLING-WAVE LINEAR ACCELERATOR FOR ELECTRONS [J].
FRY, DW ;
HARVIE, RBRS ;
MULLETT, LB ;
WALKINSHAW, W .
NATURE, 1947, 160 (4063) :351-353
[29]   Tumor response to radiotherapy regulated by endothelial cell apoptosis [J].
Garcia-Barros, M ;
Paris, F ;
Cordon-Cardo, C ;
Lyden, D ;
Rafii, S ;
Haimovitz-Friedman, A ;
Fuks, Z ;
Kolesnick, R .
SCIENCE, 2003, 300 (5622) :1155-1159
[30]   HIF-1 as a target for drug development [J].
Giaccia, A ;
Siim, BG ;
Johnson, RS .
NATURE REVIEWS DRUG DISCOVERY, 2003, 2 (10) :803-811