Necrotising enterocolitis

被引：811

作者：

Lin, Patricia W. ^{[1
]}

Stoll, Barbara J. ^{[1
]}

机构：

[1] Emory Univ, Sch Med, Dept Pediat, Div Neonatal Perinatal Med, Atlanta, GA 30322 USA

来源：

LANCET | 2006年 / 368卷 / 9543期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0140-6736(06)69525-1

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Necrotising enterocolitis is one of the most common gastrointestinal emergencies in newborn infants. Here we review the epidemiology, clinical presentation, and pathophysiology of the disease, as well as strategies for diagnosis, management, and prevention. Necrotising enterocolitis is one of the most devastating and unpredictable diseases affecting premature infants. Despite decades of research, its pathogenesis remains unclear; diagnosis can be difficult; and treatment is challenging. We will need to improve our understanding of intestinal defences in premature infants, dietary and bacterial factors, and genetic effects that could predispose infants to necrotising enterocolitis before we can develop new strategies for prevention and treatment.

引用

页码：1271 / 1283

页数：13

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