Simultaneous recordings were made of ear and tail blood flow during alerting responses to salient environmental stimuli in conscious rabbits, and during electrical stimulation of the spinal trigeminal tract and raphe pallidus in anesthetized rabbits. Blood flow fell in a highly correlated manner (Pearson coefficient ranging from 0.52 to 0.95) in these experimental situations. Salient stimuli in conscious rabbits, and noxious stimuli in anesthetized rabbits appear to cause a generalized vasoconstriction in cutaneous beds. (C) 1999 Published by Elsevier Science B.V. All rights reserved.