Discrimination between normal and malignant human gastric tissues by Fourier transform infrared spectroscopy

被引：139

作者：

Fujioka, N

Morimoto, Y

Arai, T

Kikuchi, M

机构：

[1] Natl Def Med Coll, Dept Med Engn, Tokorozawa, Saitama 3598513, Japan

[2] Keio Univ, Fac Sci & Technol, Dept Appl Phys & Physicoinformat, Yokohama, Kanagawa 2238522, Japan

来源：

CANCER DETECTION AND PREVENTION | 2004年 / 28卷 / 01期

关键词：

gastric cancer; cancer diagnosis; discriminant analysis;

D O I：

10.1016/j.cdp.2003.11.004

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The aim of this study was to determine whether malignant and normal human gastric tissues can be distinguished by Fourier transform infrared (FTIR) spectroscopy. Compared with normal tissue, malignant tissues showed significant increases in infrared (IR) absorption in 10 bands lying in a region of 925-1660 cm(-1). Using the 10 IR absorption bands as markers, discriminant analysis was carried out for tissue discrimination. As a result, 22 out of the 23 gastric cancer samples and 9 out of the 12 gastric normal samples were correctly segregated, yielding 88.6% accuracy. The present results suggest that FTIR spectroscopy is a useful tool for screening gastric cancer. (C) 2004 International Society for Preventive Oncology. Published by Elsevier Ltd. All rights reserved.

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收藏

页码：32 / 36

页数：5

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