Structure of a multidrug transporter

被引:59
作者
Gottesman, Michael M. [1 ]
Ambudkar, Suresh V. [1 ]
Xia, Di [1 ]
机构
[1] NCI, Cell Biol Lab, NIH, Bethesda, MD 20892 USA
关键词
P-GLYCOPROTEIN; MOLECULAR-BASIS; RESISTANCE; PROTEINS; HOMOLOGY; CELLS; MDR1; GENE;
D O I
10.1038/nbt0609-546
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Crystal structures of a mammalian multidrug efflux pump bound to peptide inhibitors may reveal drug-binding sites.
引用
收藏
页码:546 / 547
页数:2
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