Molecularly imprinted uniform-sized polymer-based stationary phase for naproxen

被引：30

作者：

Haginaka, J ^{[1
]}

Takehira, H ^{[1
]}

Hosoya, K ^{[1
]}

Tanaka, N ^{[1
]}

机构：

[1] KYOTO INST TECHNOL, DEPT POLYMER SCI & ENGN, SAKYO KU, KYOTO 606, JAPAN

来源：

CHEMISTRY LETTERS | 1997年 / 06期

关键词：

D O I：

10.1246/cl.1997.555

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A molecularly imprinted uniform-sized polymer-based stationary phase for (S)-naproxen has been prepared using 4-vinylpyridine and ethylenedimethacrylate as a host functional monomer and cross-linker, respectively. The imprinted polymer material could separate naproxen enantiomers with separation factor of 1.74. Further, the materials showed high selectivity for naproxen and moderate selectivity for other 2-arylpropionic acid derivatives. On the other hand, the imprinted polymer material showed little selectivity for other acidic, basic and neutral compounds.

引用

页码：555 / 556

页数：2

共 10 条

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