Giant proteins that move DNA:: bullies of the genomic playground

被引：43

作者：

Cozzarelli, Nicholas R. ^{[1
]}

Cost, Gregory J. ^{[1
]}

Nöllmann, Marcelo ^{[1
]}

Viard, Thierry ^{[1
]}

Stray, James E. ^{[1
]}

机构：

[1] Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2006年 / 7卷 / 08期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1038/nrm1982

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

As genetic material DNA is wonderful, but as a macromolecule it is unruly, voluminous and fragile. Without the action of DNA replicases, topoisomerases, helicases, translocases and recombinases, the genome would collapse into a topologically entangled random coil that would be useless to the cell. We discuss the organization, movement and energetics of these proteins that are crucial to the preservation of a molecule that has such beautiful biological but challenging physical properties.

引用

页码：580 / 588

页数：9

共 75 条

[31] A moving DNA replication factory in Caulobacter crescentus [J].

Jensen, RB ;

Wang, SC ;

Shapiro, L .

EMBO JOURNAL, 2001, 20 (17) :4952-4963

[32] Cellular DNA replicases: Components and dynamics at the replication fork [J].

Johnson, A ;

O'Donnell, M .

ANNUAL REVIEW OF BIOCHEMISTRY, 2005, 74 :283-315

[33] Mitotic spindle assembly and chromosome segregation: Refocusing on microtubule dynamics [J].

Kline-Smith, SL ;

Walczak, CE .

MOLECULAR CELL, 2004, 15 (03) :317-327

[34] Ligands for clathrin-mediated endocytosis are differentially sorted into distinct populations of early endosomes [J].

Lakadamyali, M ;

Rust, MJ ;

Zhuang, XW .

CELL, 2006, 124 (05) :997-1009

[35] Spatial and temporal organization of replicating Escherichia coli chromosomes [J].

Lau, IF ;

Filipe, SR ;

Soballe, B ;

Okstad, OA ;

Barre, FX ;

Sherratt, DJ .

MOLECULAR MICROBIOLOGY, 2003, 49 (03) :731-743

[36] ATPase switches controlling DNA replication initiation [J].

Lee, DG ;

Bell, SP .

CURRENT OPINION IN CELL BIOLOGY, 2000, 12 (03) :280-285

[37] Movement of replicating DNA through a stationary replisome [J].

Lemon, KP ;

Grossman, AD .

MOLECULAR CELL, 2000, 6 (06) :1321-1330

[38] Identification of oligonucleotide sequences that direct the movement of the Escherichia coli FtsK translocase [J].

Levy, O ;

Ptacin, JL ;

Pease, PJ ;

Gore, J ;

Eisen, MB ;

Bustamante, C ;

Cozzarelli, NR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (49) :17618-17623

[39] Compartmentalization of transcription and translation in Bacillus subtilis [J].

Lewis, PJ ;

Thaker, SD ;

Errington, J .

EMBO JOURNAL, 2000, 19 (04) :710-718

[40] Direct observation of DNA distortion by the RSC complex [J].

Lia, G ;

Praly, E ;

Ferreira, H ;

Stockdale, C ;

Tse-Dinh, YC ;

Dunlap, D ;

Croquette, V ;

Bensimon, D ;

Owen-Hughes, T .

MOLECULAR CELL, 2006, 21 (03) :417-425

← 1 2 3 4 5 6 7 8 →