Pulsed near-infrared laser diode excitation system for biomedical photoacoustic imaging

被引：144

作者：

Allen, Thomas J. ^{[1
]}

Beard, Paul C. ^{[1
]}

机构：

[1] UCL, Dept Med Phys & Bioengn, London WC1E 6BT, England

来源：

OPTICS LETTERS | 2006年 / 31卷 / 23期

关键词：

D O I：

10.1364/OL.31.003462

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

A pulsed laser diode system operating at 905 nm has been developed for the generation of photoacoustic signals in tissue. It was evaluated by measuring the photoacoustic waveforms generated in a blood vessel phantom comprising three dye-filled (mu(alpha)= 1 mm(-1)) tubes of diameters 120-580)mu m immersed to a maximum depth of 9 mm in a turbid liquid (mu(s)'= 1 mm(-1)). The system was then combined with a cylindrical scanning system to obtain two-dimensional images of a tissue phantom. The signal-to-noise ratio of the detected signals in both cases and the image contrast in the latter suggest that such a system could provide a compact and inexpensive alternative to current excitation sources for superficial imaging applilcations. (c) 2006 Optical Society of America.

引用

页码：3462 / 3464

页数：3

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