Neuroscience - Memory - a century of consolidation

被引:2990
作者
McGaugh, JL [1 ]
机构
[1] Univ Calif Irvine, Ctr Neurobiol Learning & Memory, Irvine, CA 92697 USA
[2] Univ Calif Irvine, Dept Neurobiol & Behav, Irvine, CA 92697 USA
关键词
D O I
10.1126/science.287.5451.248
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The memory consolidation hypothesis proposed 100 years ago by Muller and Pilzecker continues to guide memory research. The hypothesis that new memories consolidate slowly over time has stimulated studies revealing the hormonal and neural influences regulating memory consolidation, as well as molecular and cellular mechanisms. This review examines the progress made over the century in understanding the time-dependent processes that create our lasting memories.
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页码:248 / 251
页数:4
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