Effects of Glycyrrhiza glabra polysaccharides on immune and antioxidant activities in high-fat mice

被引：100

作者：

Hong, Ying-Kai ^{[2
]}

Wu, Hua-Tao ^{[3
]}

Ma, Tao ^{[3
]}

Liu, Wei-Juan ^{[1
]}

He, Xue-Jun ^{[2
]}

机构：

[1] Shantou Univ, Coll Med, Affiliated Hosp 1, Dept Burn Surg, Shantou, Guangdong, Peoples R China

[2] Shantou Univ, Coll Med, Affiliated Hosp 1, Dept Urol, Shantou, Guangdong, Peoples R China

[3] Shantou Univ, Coll Med, Affiliated Hosp 1, Dept Gen Surg, Shantou, Guangdong, Peoples R China

来源：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2009年 / 45卷 / 01期

关键词：

Mice; High-fat; Glycyrrhiza glabra polysaccharides; GENOTOXICITY; METABOLISM; CULTURES; STRESS;

D O I：

10.1016/j.ijbiomac.2009.04.001

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The purpose of this study was to investigate the immune and antioxidant activities of Glycyrrhiza glabra polysaccharides (GGP) in rats fed high-fat diet. The experiment was performed on four groups of growing Kunming mice. The results of the experiment showed a statistically significant decrease in serum antioxidant enzyme activities in high-fat group. Administration of GGP dose-dependently significantly enhanced immune and antioxidant enzyme activities in the GGP-treated mice compared to the high-fat model mice. It is concluded that GGP treatment can enhance immune activities, and reduce oxidative stress in high-fat mice. (C) 2009 Elsevier B.V. All rights reserved.

引用

页码：61 / 64

页数：4

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