Proton pump inhibitors and gastric neoplasia

被引:76
作者
Kuipers, E. J. [1 ]
机构
[1] Univ Rotterdam, Med Ctr, Dept Gastroenterol & Hepatol, Erasmus MC, NL-3000 CA Rotterdam, Netherlands
关键词
D O I
10.1136/gut.2005.090514
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Proton pump inhibitors (PPIs) are very effective in maintaining symptomatic and endoscopic remission of acid peptic disorders, such as gastro-oesophageal reflux disease. Side effects with respect to function and morphology of the gastric mucosa are common. Helicobacter pylori eradication can partially prevent and reverse these effects without impairing PPI therapy for gastro-oesophageal reflux disease. This makes long term PPI treatment a safe therapy for patients with acid peptic disorders. The potential side effects of such therapy are discussed here.
引用
收藏
页码:1217 / 1221
页数:5
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