Association of KIBRA and memory

被引：63

作者：

Bates, Timothy C. ^{[1
]}

Price, Jackie F. ^{[2
]}

Harris, Sarah E. ^{[1
]}

Marioni, Riccardo E. ^{[2
]}

Fowkes, F. Gerry R. ^{[2
]}

Stewart, Marlene C. ^{[2
]}

Murray, Gordon D. ^{[2
]}

Whalley, Lawrence J. ^{[3
]}

Starr, John M. ^{[4
]}

Deary, Ian J. ^{[1
]}

机构：

[1] Univ Edinburgh, Dept Psychol, Edinburgh EH8 9JZ, Midlothian, Scotland

[2] Univ Edinburgh, Div Community Hlth Sci, Edinburgh EH8 9JZ, Midlothian, Scotland

[3] Univ Aberdeen, Dept Mental Hlth, Aberdeen AB9 1FX, Scotland

[4] Univ Edinburgh, Geriatr Med Unit, Edinburgh EH8 9JZ, Midlothian, Scotland

来源：

NEUROSCIENCE LETTERS | 2009年 / 458卷 / 03期

基金：

英国惠康基金; 英国生物技术与生命科学研究理事会; 英国医学研究理事会;

关键词：

Memory; KIBRA; AVLT; Logical memory; Association; SCOTTISH MENTAL SURVEY; FRONTOTEMPORAL DEMENTIA; COGNITIVE-ABILITY; FOLLOW-UP; OLD-AGE; RECOLLECTION; CHILDHOOD; FAMILIARITY; HIPPOCAMPUS; RETRIEVAL;

D O I：

10.1016/j.neulet.2009.04.050

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We report on the association of KIBRA with memory in two samples of older individuals assessed on either memory for semantically unrelated word stimuli (Rey Auditory Verbal Learning Test, n = 2091). or a measure of semantically related material (the WAIS Logical Memory Test of prose-passage recall, n = 542). SNP rs17070145 was associated with delayed recall of semantically unrelated items, but not with immediate recall for these stimuli, nor with either immediate or delayed recall for semantically related material. The pattern of results suggests a role for the T -> C substitution in intron 9 of KIBRA in a component of episodic memory involved in long-term storage but independent of processes shared with immediate recall such as rehearsal involved in acquisition and rehearsal or processes. (C) 2009 Published by Elsevier Ireland Ltd.

引用

页码：140 / 143

页数：4

共 27 条

[1]

*AAA, 1998, RAND CONTR TRIAL LOW

[2]

BAYLESS JD, 1995, CLIN NEUROPSYCHOLOGY, V10, P297

[3] Impaired familiarity with preserved recollection after anterior temporal-lobe resection that spares the hippocampus [J].

Bowles, Ben ;

Crupi, Carina ;

Mirsattari, Seyed M. ;

Pigott, Susan E. ;

Parrent, Andrew G. ;

Pruessner, Jens C. ;

Yonelinas, Andrew P. ;

Kohler, Stefan .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (41) :16382-16387

[4] KLOTHO genotype and cognitive ability in childhood and old age in the same individuals [J].

Deary, IJ ;

Harris, SE ;

Fox, HC ;

Hayward, C ;

Wright, AF ;

Starr, JM ;

Whalley, LJ .

NEUROSCIENCE LETTERS, 2005, 378 (01) :22-27

[5] Nicastrin gene polymorphisms, cognitive ability level and cognitive ageing [J].

Deary, IJ ;

Hamilton, G ;

Hayward, C ;

Whalley, LJ ;

Powell, J ;

Starr, JM ;

Lovestone, S .

NEUROSCIENCE LETTERS, 2005, 373 (02) :110-114

[6] Apolipoprotein E gene variability and cognitive functions at age 79: A follow-up of the Scottish Mental Survey of 1932 [J].

Deary, IJ ;

Whiteman, MC ;

Pattie, A ;

Starr, JM ;

Hayward, C ;

Wright, AF ;

Visscher, PM ;

Tynan, MC ;

Whalley, LJ .

PSYCHOLOGY AND AGING, 2004, 19 (02) :367-371

[7] The impact of childhood intelligence on later life: Following up the Scottish Mental Surveys of 1932 and 1947 [J].

Deary, IJ ;

Whiteman, MC ;

Starr, JM ;

Whalley, LJ ;

Fox, HC .

JOURNAL OF PERSONALITY AND SOCIAL PSYCHOLOGY, 2004, 86 (01) :130-147

[8] The stability of individual differences in mental ability from childhood to old age: Follow-up of the 1932 Scottish mental survey [J].

Deary, IJ ;

Whalley, LJ ;

Lemmon, H ;

Crawford, JR ;

Starr, JM .

INTELLIGENCE, 2000, 28 (01) :49-55

[9] Executive control during episodic retrieval: Multiple prefrontal processes subserve source memory [J].

Dobbins, IG ;

Foley, H ;

Schacter, DL ;

Wagner, AD .

NEURON, 2002, 35 (05) :989-996

[10] MINI-MENTAL STATE - PRACTICAL METHOD FOR GRADING COGNITIVE STATE OF PATIENTS FOR CLINICIAN [J].

FOLSTEIN, MF ;

FOLSTEIN, SE ;

MCHUGH, PR .

JOURNAL OF PSYCHIATRIC RESEARCH, 1975, 12 (03) :189-198

← 1 2 3 →