Where chaperones and nascent polypeptides meet

被引：8

作者：

Albanèse, V ^{[1
]}

Frydman, J ^{[1
]}

机构：

[1] Stanford Univ, Dept Sci Biol, Stanford, CA 94305 USA

来源：

NATURE STRUCTURAL BIOLOGY | 2002年 / 9卷 / 10期

关键词：

D O I：

10.1038/nsb1002-716

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two recent studies provide evidence for a direct interaction between the ribosomal protein L23 at the exit tunnel of the ribosome and the bacterial chaperone trigger factor, and between the eukaryotic L23 homolog and the signal recognition particle. These findings indicate that the exit site of the ribosome may physically link translation to the cytosolic components that guide nascent polypeptides to their correct fate.

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收藏

页码：716 / 718

页数：3

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