Comorbid psychiatric disorders in children with autism: Interview development and rates of disorders

被引:1061
作者
Leyfer, Ovsanna T.
Folstein, Susan E.
Bacalman, Susan
Davis, Naomi O.
Dinh, Elena
Morgan, Jubel
Tager-Flusberg, Helen
Lainhart, Janet E.
机构
[1] Utah Autism Res Program, Salt Lake City, UT 84108 USA
[2] Univ Louisville, Dept Psychol & Brain Sci, Louisville, KY 40292 USA
[3] Johns Hopkins Univ, Dept Psychiat, Baltimore, MD USA
[4] Univ Calif Davis, MIND Inst, Sacramento, CA 95817 USA
[5] Univ Massachusetts, Dept Psychol, Boston, MA 02125 USA
[6] Boston Univ, Sch Med, Dept Anat & Neurobiol, Boston, MA 02215 USA
[7] Univ Utah, Sch Med, Dept Psychiat, Salt Lake City, UT 84112 USA
关键词
psychopathology; autism; psychiatric interview; comorbidity;
D O I
10.1007/s10803-006-0123-0
中图分类号
B844 [发展心理学(人类心理学)];
学科分类号
040202 ;
摘要
The Kiddie Schedule for Affective Disorders and Schizophrenia was modified for use in children and adolescents with autism by developing additional screening questions and coding options that reflect the presentation of psychiatric disorders in autism spectrum disorders. The modified instrument, the Autism Comorbidity Interview-Present and Lifetime Version (ACI-PL), was piloted and frequently diagnosed disorders, depression, ADHD, and OCD, were tested for reliability and validity. The ACI-PL provides reliable DSM diagnoses that are valid based on clinical psychiatric diagnosis and treatment history. The sample demonstrated a high prevalence of specific phobia, obsessive compulsive disorder, and ADHD. The rates of psychiatric disorder in autism are high and are associated with functional impairment.
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页码:849 / 861
页数:13
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