The control of T cell responses by dendritic cell subsets

被引：211

作者：

Reid, SD ^{[1
]}

Penna, G ^{[1
]}

Adorini, L ^{[1
]}

机构：

[1] Roche Milao Ric, I-20132 Milan, Italy

来源：

CURRENT OPINION IN IMMUNOLOGY | 2000年 / 12卷 / 01期

关键词：

D O I：

10.1016/S0952-7915(99)00059-X

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Dendritic cells are known as the most efficient antigen-presenting cell type to activate naive T cells; however, they are able to do more than just efficiently present antigen to T cells. They are key modulators of the immune response that can influence Th cell differentiation by preferentially inducing Th type 1 or 2 cell responses, and the differential polarisation of CD4(+) T cells appears to be mediated by discrete dendritic cell subsets.

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页码：114 / 121

页数：8

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