Organocatalytic regioselective Michael additions of cyclic enones via asymmetric phase transfer catalysis

被引：18

作者：

Ceccarelli, Roberto

Insogna, Susanna

Bella, Marco

机构：

[1] Univ Roma La Sapienza, Dipartimento Chim, I-00185 Rome, Italy

[2] Univ Roma La Sapienza, CNR, Ist Chim Biomol, Sez Roma, I-00185 Rome, Italy

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2006年 / 4卷 / 23期

关键词：

D O I：

10.1039/b612606e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Cyclohexanone and cycloheptanone can be enantioselectively functionalized in the 3-position with up to 92% ee and 87% ee, respectively, by the base-promoted dimerization of the corresponding enones using 3,4,5-tribenzyloxybenzyl cinchoninium bromide, as a new effective catalyst.

引用

页码：4281 / 4284

页数：4

共 28 条

[1]

[Anonymous], 1997, PHASE TRANSFER CATAL

[2]

BERKESSEL A, 2005, ASYMMETRIC ORGANOCAT, pCH3

[3] Chirally aminated 2-naphthols-organocatalytic synthesis of non-biaryl atropisomers by asymmetric Friedel-Crafts amination [J].