Toward performing transplantation in highly sensitized patients

被引:20
作者
Fuggle, SV [1 ]
Martin, S
机构
[1] Churchill Hosp, Oxford Transplant Ctr, Oxford OX3 7LJ, England
[2] Manchester Royal Infirm, Transplantat Lab, Manchester M13 9WL, Lancs, England
[3] UK Transplant Serv, Bristol BS10 5ND, Avon, England
[4] Univ Oxford, Nuffield Dept Surg, Oxford, England
关键词
renal transplantation; highly sensitized patients;
D O I
10.1097/01.tp.0000129257.34967.12
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Performing transplantation in highly sensitized patients represents a challenge for transplant units and organ exchange organizations. There are various approaches that can be adopted in order to transplant these patients, either through kidney exchange programs or by using desensitization protocols. In this article we discuss a number of these approaches, including the system currently used in the United Kingdom. The system encourages understanding of the patient's antibody profile and has resulted in a threefold increase in the number of highly sensitized patients undergoing transplantation.
引用
收藏
页码:186 / 189
页数:4
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