Detection of trace CuII by a designed calix[4]arene based fluorescent reagent

被引：18

作者：

Ma, HM ^{[1
]}

Ma, QL ^{[1
]}

Su, MH ^{[1
]}

Nie, LH ^{[1
]}

Han, HW ^{[1
]}

Xiong, SX ^{[1
]}

Xin, B ^{[1
]}

Liu, GQ ^{[1
]}

机构：

[1] Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China

来源：

NEW JOURNAL OF CHEMISTRY | 2002年 / 26卷 / 10期

关键词：

D O I：

10.1039/b203331c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A highly Cu2+ selective calix [4] arene based uorescent reagent, 5,17-bis(4-methylcoumarin-7-azo)-25,26,27,28-tetrahydroxycalix [ 4] arene, has been designed, synthesized and evaluated. The reagent exhibits excellent selectivity for Cu2+ over a wide range of alkali, alkaline earth and other transition metal ions. Quenching of its fluorescence due to a strong Cu2+ affinity, induced binding and selective redox reaction is not influenced by the presence of 20- to 10000-fold excesses of Al3+, Ca2+, Cd2+, Co2+, Cr3+, Hg2+, K+, Mg2+, Mn2+, NH4+, Ni2+, Pb2+, Zn2+, Cl-, NO3-, CO32-, SO42- or PO43-. Furthermore, with this uorescent reagent a simple, sensitive and highly selective method has been developed for measuring trace Cu2+ in real biological fluids. The combination of multiple selective responses presented here may provide a useful design strategy for preparing selective reagents of other species.

引用

页码：1456 / 1460

页数：5

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