JM-PHOS ligands: Second-generation phosphine oxazolines for asymmetric catalysis

被引：53

作者：

Hou, DR ^{[1
]}

Burgess, K ^{[1
]}

机构：

[1] Texas A&M Univ, Dept Chem, College Stn, TX 77842 USA

来源：

ORGANIC LETTERS | 1999年 / 1卷 / 11期

关键词：

D O I：

10.1021/ol991008k

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A small library of phosphine oxazoline ligands 2 was prepared and tested in palladium mediated allylation processes (reactions 1 and 2). They were found to be superior to the first generation ligands 1 and as effective as the well known phosphine oxazolines 3.

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页码：1745 / 1747

页数：3

相关论文

共 14 条

[1]

28Matt P., 1994, Tetrahedron Asym, V5, P573

[2] Pd-Catalyzed asymmetric allylic alkylations using various diphenylphosphino(oxazolinyl)ferrocene ligands [J].

Ahn, KH ;

Cho, CW ;

Park, JW ;

Lee, SW .

TETRAHEDRON-ASYMMETRY, 1997, 8 (08) :1179-1185

[3] ASYMMETRIC PALLADIUM-CATALYZED ALLYLIC SUBSTITUTION USING PHOSPHORUS-CONTAINING OXAZOLINE LIGANDS [J].

DAWSON, GJ ;

FROST, CG ;

WILLIAMS, JMJ .

TETRAHEDRON LETTERS, 1993, 34 (19) :3149-3150

[4] Enantioselective catalysis with complexes of asymmetric P,N-chelate ligands [J].

Helmchen, G ;

Kudis, S ;

Sennhenn, P ;

Steinhagen, H .

PURE AND APPLIED CHEMISTRY, 1997, 69 (03) :513-518

[5]

Jandeleit B, 1998, CHEM IND-LONDON, P795

[6]

Jandeleit B., 1998, CATTECH, V2, P101

[7] Ortho-substituted benzofused macrocyclic lactams as zinc metalloprotease inhibitors [J].

Ksander, GM ;

deJesus, R ;

Yuan, A ;

Ghai, RD ;

Trapani, A ;

McMartin, C ;

Bohacek, R .

JOURNAL OF MEDICINAL CHEMISTRY, 1997, 40 (04) :495-505

[8] Design and optimization of new phosphine oxazoline ligands via high-throughput catalyst screening [J].

Porte, AM ;

Reibenspies, J ;

Burgess, K .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1998, 120 (36) :9180-9187

[9] Systematic modification of the separation selectivity of cyclodextrin-based gas chromatographic stationary phases by varying the size of the 6-O-substituents [J].

Shitangkoon, A ;

Vigh, G .

JOURNAL OF CHROMATOGRAPHY A, 1996, 738 (01) :31-42

[10] CATALYSIS OF ALLYLIC SUBSTITUTIONS BY PD COMPLEXES OF OXAZOLINES CONTAINING AN ADDITIONAL P, S, OR SE CENTER - X-RAY CRYSTAL-STRUCTURES AND SOLUTION STRUCTURES OF CHIRAL PI-ALLYL PALLADIUM COMPLEXES OF PHOSPHINOARYLOXAZOLINES [J].

SPRINZ, J ;

KIEFER, M ;

HELMCHEN, G ;

HUTTNER, G ;

WALTER, O ;

ZSOLNAI, L ;

REGGELIN, M .

TETRAHEDRON LETTERS, 1994, 35 (10) :1523-1526