Regulation of endocytic traffic by Rho family GTPases

被引:177
作者
Ellis, S [1 ]
Mellor, H [1 ]
机构
[1] Univ Bristol, Sch Med Sci, Dept Biochem, Bristol BS8 1TD, Avon, England
关键词
D O I
10.1016/S0962-8924(99)01710-9
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Endocytosis is a complicated yet highly efficient process that involves the uptake and processing of cargoes, ranging from small molecules, to activated signalling receptors, to whole microorganisms. Regulation of endocytic pathways is poorly understood. Recent evidence suggests that the Rho GTPase family of signalling protein is intimately involved in endocytic traffic, providing novel insights into the control mechanisms that govern this process.
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页码:85 / 88
页数:4
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