Gastroesophageal Reflux Disease and Morbid Obesity: Is There a Relation?

被引：17

作者：

Fisichella, Piero M. ^{[1
]}

Patti, Marco G. ^{[2
]}

机构：

[1] Loyola Univ, Med Ctr, Stritch Sch Med, Dept Surg, Maywood, IL 60153 USA

[2] Univ Chicago, Dept Surg, Chicago, IL 60637 USA

来源：

WORLD JOURNAL OF SURGERY | 2009年 / 33卷 / 10期

关键词：

LAPAROSCOPIC NISSEN FUNDOPLICATION; LOWER ESOPHAGEAL SPHINCTER; BRISTOL HELICOBACTER PROJECT; BODY-MASS INDEX; BARIATRIC SURGERY; GASTRIC BYPASS; MOTILITY DISORDERS; BARRETTS-ESOPHAGUS; ACID EXPOSURE; RISK;

D O I：

10.1007/s00268-009-0045-z

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Gastroesophageal reflux disease (GERD) is highly prevalent in morbidly obese patients, and a high body mass index (BMI) is a risk factor for the development of GERD. However, the mechanism by which the BMI affects esophageal acid exposure is not completely understood. Although many advances have been made in the understanding of the pathophysiology of GERD, many aspects of the pathophysiology of this disease in morbidly obese patients remain unclear. The following review describes the current evidence linking esophageal reflux to obesity, covering the pathophysiology of the disease and the implications for treatment of GERD in the obese patient.

引用

页码：2034 / 2038

页数：5

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