Low-intensity pulsed ultrasound accelerates the regeneration of the sciatic nerve after neurotomy in rats

被引:88
作者
Crisci, AR [1 ]
Ferreira, AL [1 ]
机构
[1] Univ Sao Paulo, Dept Bioengn, Sao Carlos Engn Sch, Sao Paulo, Brazil
关键词
low-intensity pulsed ultrasound; peripheral nerve; regeneration;
D O I
10.1016/S0301-5629(02)00576-8
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
The biophysical qualities of pulsed ultrasound (US) led us to appraise its effect on the regeneration of a peripheral nerve. In this study, our intention was to evaluate the effects of pulsed US on the axotomy of the sciatic nerve in rats. The proximal stump of the nerve was stimulated on 12 consecutive days with pulsed US and the effects of the sonication were evaluated through morphological and morphometric techniques. Our findings suggest that sonication leads to a rapid regeneration of the nerve after axotomisation. These affirmations are based on the counting of different types of fibre components in mixed nerves and the morphological recovery of the same in comparison with nerves of animals submitted to sham operation. (E-mail: criscicozac@netsite.com.br) (C) 2002 World Federation for Ultrasound in Medicine Biology.
引用
收藏
页码:1335 / 1341
页数:7
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