Prevalence of anxiety in adults with diabetes - A systematic review

被引:399
作者
Grigsby, AB
Anderson, RJ
Freedland, KE
Clouse, RE
Lustman, PJ
机构
[1] Washington Univ, Sch Med, Dept Psychiat, St Louis, MO 63110 USA
[2] Washington Univ, Sch Med, Dept Med, St Louis, MO 63110 USA
[3] Dept Vet Affairs Med Ctr, St Louis, MO USA
基金
美国国家卫生研究院;
关键词
diabetes mellitus; anxiety disorder; prevalence;
D O I
10.1016/S0022-3999(02)00417-8
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Background: Anxiety is associated with decreased functioning and quality of life. It may have added importance in diabetes for its potential adverse effects on regimen adherence and glycemic control. Objective: To estimate the prevalence of clinically significant anxiety in adults with diabetes. Research Design and Methods: MEDLINE and PsycINFO databases and published reference lists were searched to identify studies that determined the prevalence of anxiety in diabetes from threshold scores on self-report measures or from diagnostic interviews. Prevalence was calculated as an aggregate mean weighted by the combined number of subjects in the included studies. Results: Eighteen studies having a combined population (N) of 4076 (2584 diabetic subjects, 1492 controls) satisfied the inclusion criteria. Most did not adjust for the effects of moderator variables such as gender, and only one was community-based. Generalized anxiety disorder (GAD) was present in 14% of patients with diabetes. The subsyndromal presentation of anxiety disorder not otherwise specified and of elevated anxiety symptoms were found in 27% and 40%, respectively, of patients with diabetes. The prevalence of elevated symptoms was significantly higher in women compared to men (55.3% vs. 32.9%, P<.0001) and similar in patients with Type 1 vs. Type 2 diabetes (41.3% vs. 42.2%, P=.80). Conclusion: GAD is present in 14% and elevated symptoms of anxiety in 40% of patients with diabetes who participate in clinical studies. Additional epidemiological studies are needed to determine the prevalence of anxiety in the broader population of persons with diabetes. (C) 2002 Elsevier Science Inc. All rights reserved.
引用
收藏
页码:1053 / 1060
页数:8
相关论文
共 81 条
[41]   EFFECTS OF ALPRAZOLAM ON GLUCOSE REGULATION IN DIABETES - RESULTS OF A DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL [J].
LUSTMAN, PJ ;
GRIFFITH, LS ;
CLOUSE, RE ;
FREEDLAND, KE ;
EISEN, SA ;
RUBIN, EH ;
CARNEY, RM ;
MCGILL, JB .
DIABETES CARE, 1995, 18 (08) :1133-1139
[42]  
LUSTMAN PJ, 1983, LANCET, V1, P588
[43]   RELATIONSHIP OF PSYCHIATRIC-ILLNESS TO IMPOTENCE IN MEN WITH DIABETES [J].
LUSTMAN, PJ ;
CLOUSE, RE .
DIABETES CARE, 1990, 13 (08) :893-895
[44]   EFFECTS OF INSULIN AND STREPTOZOTOCIN-INDUCED DIABETES ON BRAIN TRYPTOPHAN AND SEROTONIN METABOLISM IN RATS [J].
MACKENZIE, RG ;
TRULSON, ME .
JOURNAL OF NEUROCHEMISTRY, 1978, 30 (01) :205-211
[45]   SCHEDULE FOR AFFECTIVE-DISORDERS AND SCHIZOPHRENIA - LIFETIME VERSION MODIFIED FOR THE STUDY OF ANXIETY DISORDERS (SADS-LA) - RATIONALE AND CONCEPTUAL DEVELOPMENT [J].
MANNUZZA, S ;
FYER, AJ ;
KLEIN, DF ;
ENDICOTT, J .
JOURNAL OF PSYCHIATRIC RESEARCH, 1986, 20 (04) :317-325
[46]  
MCGRADY A, 2001, APPL PSYCHOPHYS BIOF, V24, P79
[47]   Quality of life in individuals with anxiety disorders [J].
Mendlowicz, MV ;
Stein, MB .
AMERICAN JOURNAL OF PSYCHIATRY, 2000, 157 (05) :669-682
[48]   Treatment typically provided for comorbid anxiety disorders [J].
Meredith, LS ;
Sherbourne, CD ;
Jackson, CA ;
Camp, P ;
Wells, KB .
ARCHIVES OF FAMILY MEDICINE, 1997, 6 (03) :231-237
[49]   Diagnostic and Statistical Manual of Mental Disorders [J].
Mittal, Vijay A. ;
Walker, Elaine F. .
PSYCHIATRY RESEARCH, 2011, 189 (01) :158-159
[50]   PSYCHOSOCIAL CORRELATES OF HEMOGLOBIN A1C IN YOUNG-ADULTS WITH TYPE-I DIABETES [J].
NIEMCRYK, SJ ;
SPEERS, MA ;
TRAVIS, LB ;
GARY, HE .
JOURNAL OF PSYCHOSOMATIC RESEARCH, 1990, 34 (06) :617-627