Retrograde transport from endosomes to the trans-Golgi network

被引:508
作者
Bonifacino, Juan S. [1 ]
Rojas, Raul [1 ]
机构
[1] NICHHD, Cell Biol & Metab Branch, NIH, Bethesda, MD 20892 USA
关键词
D O I
10.1038/nrm1985
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
A subset of intracellular transmembrane proteins such as acid-hydrolase receptors, processing peptidases and SNAREs, as well as extracellular protein toxins such as Shiga toxin and ricin, undergoes 'retrograde' transport from endosomes to the trans-Golgi network. Here, we discuss recent studies that have begun to unravel the molecular machinery that is involved in this process. We also propose a central role for a 'tubular endosomal network' in sorting to recycling pathways that lead not only to the trans-Golgi network but also to different plasma-membrane domains and to specialized storage vesicles.
引用
收藏
页码:568 / 579
页数:12
相关论文
共 99 条
[41]   Efficient endosome-to-Golgi transport of Shiga toxin is dependent on dynamin and clathrin [J].
Lauvrak, SU ;
Torgersen, ML ;
Sandvig, K .
JOURNAL OF CELL SCIENCE, 2004, 117 (11) :2321-2331
[42]   Specific retrieval of the exocytic SNARE Snc1p from early yeast endosomes [J].
Lewis, MJ ;
Nichols, BJ ;
Prescianotto-Baschong, C ;
Riezman, H ;
Pelham, HRB .
MOLECULAR BIOLOGY OF THE CELL, 2000, 11 (01) :23-38
[43]   Mutation of the Rab6 homologue of Saccharomyces cerevisiae, YPT6, inhibits both early Golgi function and ribosome biosynthesis [J].
Li, BJ ;
Warner, JR .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (28) :16813-16819
[44]   Rme-1 regulates the distribution and function of the endocytic recycling compartment in mammalian cells [J].
Lin, SX ;
Grant, B ;
Hirsh, D ;
Maxfield, FR .
NATURE CELL BIOLOGY, 2001, 3 (06) :567-572
[45]   RAB9 FUNCTIONS IN TRANSPORT BETWEEN LATE ENDOSOMES AND THE TRANS GOLGI NETWORK [J].
LOMBARDI, D ;
SOLDATI, T ;
RIEDERER, MA ;
GODA, Y ;
ZERIAL, M ;
PFEFFER, SR .
EMBO JOURNAL, 1993, 12 (02) :677-682
[46]   Autoantigen golorin-97, an effector of Arl1 GTPase, participates in traffic from the endosome to the Trans-golgi network [J].
Lu, L ;
Tai, GH ;
Hong, WJ .
MOLECULAR BIOLOGY OF THE CELL, 2004, 15 (10) :4426-4443
[47]   Biochemical and genetic evidence for the involvement of yeast Ypt6-GTPase in protein retrieval to different Golgi compartments [J].
Luo, ZL ;
Gallwitz, D .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (02) :791-799
[48]   Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform [J].
Mallard, F ;
Tang, BL ;
Galli, T ;
Tenza, D ;
Saint-Pol, A ;
Yue, X ;
Antony, C ;
Hong, WJ ;
Goud, B ;
Johannes, L .
JOURNAL OF CELL BIOLOGY, 2002, 156 (04) :653-664
[49]   Direct pathway from early/recycling endosomes to the Golgi apparatus revealed through the study of Shiga toxin B-fragment transport [J].
Mallard, F ;
Antony, C ;
Tenza, D ;
Salamero, J ;
Goud, B ;
Johannes, L .
JOURNAL OF CELL BIOLOGY, 1998, 143 (04) :973-990
[50]   THE SORTING RECEPTOR FOR YEAST VACUOLAR CARBOXYPEPTIDASE-Y IS ENCODED BY THE VPS10 GENE [J].
MARCUSSON, EG ;
HORAZDOVSKY, BF ;
CEREGHINO, JL ;
GHARAKHANIAN, E ;
EMR, SD .
CELL, 1994, 77 (04) :579-586