Symmetry and the energy landscapes of biomolecules

被引：171

作者：

Wolynes, PG

机构：

[1] School of Chemical Sciences, Univ. of Illinois, Urbana-Champaign, Urbana

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1996年 / 93卷 / 25期

关键词：

D O I：

10.1073/pnas.93.25.14249

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The role of symmetry in the folding of proteins is discussed using energy landscape theory. An analytical argument shows it is much easier to find sequences with funneled energy landscape capable of fast folding if the structure is symmetric. The analogy with phase transitions of small clusters with magic numbers is discussed.

引用

页码：14249 / 14255

页数：7