Tipping the scales of selection with BAFF

被引:8
作者
Cancro, MP [1 ]
机构
[1] Univ Penn, Sch Med, Dept Pathol & Lab Med, Philadelphia, PA 19104 USA
关键词
D O I
10.1016/j.immuni.2004.06.001
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Two recent Immunity papers (Lesley et al., 2004; Thien et al., 2004) link peripheral tolerance with the ability of developing B cells to capture BAFF. These findings suggest that an increase in effective BAFF levels leads to autoreactive B cell maturation.
引用
收藏
页码:655 / 656
页数:2
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