A method for the stereospecific conversion of 1,3-diols into oxetanes

被引：7

作者：

Aftab, T ^{[1
]}

Carter, C ^{[1
]}

Hart, J ^{[1
]}

Nelson, A ^{[1
]}

机构：

[1] Univ Leeds, Sch Chem, Leeds LS2 9JT, W Yorkshire, England

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 49期

关键词：

D O I：

10.1016/S0040-4039(99)01840-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Diastereomerically pure 1,3-diols were converted into the corresponding orthoesters and reacted with acetyl bromide to give bromoacetates with inversion of configuration at a benzylic position. Methanolysis and cyclisation gave diastereomerically pure 2,4-disubstituted oxetanes. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：8679 / 8683

页数：5

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