Fabrication of nanostructured polymeric surfaces for biosensing devices

被引：80

作者：

Valsesia, A ^{[1
]}

Colpo, P ^{[1
]}

Silvan, MM ^{[1
]}

Meziani, T ^{[1
]}

Ceccone, G ^{[1
]}

Rossi, F ^{[1
]}

机构：

[1] Commiss European Communities, Joint Res Ctr, Inst Hlth & Consumer Protect, I-21020 Ispra, VA, Italy

来源：

NANO LETTERS | 2004年 / 4卷 / 06期

关键词：

D O I：

10.1021/nl0496567

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this paper a method for fabricating nanostructured polymeric surfaces with contrasted chemical functionality is presented. First, a polymer film of acrylic acid (PAA) is deposited by plasma enhanced chemical vapor deposition. It is covered by a monolayer of particles in the 500 nm range. Then oxygen plasma etching is performed, providing etching of both nanoparticles and acrylic acid film present between the masks. The etching process is stopped before the complete etching of the nanoparticles and the residual ones are removed by ultrasonic bath. Chemical contrast is thus created between nanodomes having plateau-like surface with as-deposited carboxylic functionality and substrate surface. Protein attachment experiments show that proteins are selectively bound to the functional plateau of the PAA domes.

引用

页码：1047 / 1050

页数：4

共 6 条

[1] ULTRA-SMALL METAL-PARTICLE ARRAYS PRODUCED BY HIGH-RESOLUTION ELECTRON-BEAM LITHOGRAPHY [J].