Thin Film Elastic Modulus of Degradable Tyrosine-Derived Polycarbonate Biomaterials and Their Blends

被引：13

作者：

Aamer, Khaled A. ^{[1
]}

Stafford, Christopher M. ^{[1
]}

Richter, Lee J. ^{[2
]}

Kohn, Joachim ^{[3
]}

Becker, Matthew L. ^{[1
]}

机构：

[1] NIST, Div Polymers, Gaithersburg, MD 20899 USA

[2] NIST, Surface & Microanal Sci Div, Gaithersburg, MD 20899 USA

[3] Rutgers State Univ, New Jersy Ctr Biomat, Piscataway, NJ 08854 USA

来源：

MACROMOLECULES | 2009年 / 42卷 / 04期

关键词：

MECHANICAL-PROPERTIES; RELAXATION MECHANISMS; GLASS-TRANSITION; POLYMER; POLYARYLATES; SCAFFOLDS;

D O I：

10.1021/ma802115b

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

The integrity, function, and performance of biomedical devices having thin polymeric coatings are critically dependent on the mechanical properties of the film, including the elastic modulus. In this report, the elastic moduli of several tyrosine-derived polycarbonate thin films, specifically desaminotyrosyl ethyl tyrosine polycarbonates p(DTE carbonate), an iodinated derivative P(I-2-DTE carbonate), and several discrete blends are measured using a method based on surface wrinkling. The data shows that the elastic modulus does not vary significantly with the blend composition as the weight percentage Of P(I-2-DTE carbonate) increases for films of uniform thickness in the range of 67 to 200 nm. As a function of film thickness, the observed elastic moduli of p(DTE carbonate), p(I-2-DTE carbonate) and their 50:50 by mass blend show little variation over the range 30 to 200 nm.

引用

页码：1212 / 1218

页数：7

共 39 条

[1] Cellular response to phase-separated blends of tyrosine-derived polycarbonates [J].