Homocysteine: Is it a clinically important cardiovascular risk factor?

被引：77

作者：

Lentz, SR

Haynes, WG

机构：

[1] Univ Iowa, Dept Internal Med, Gen Clin Res Ctr, Iowa City, IA 52242 USA

[2] Vet Affairs Med Ctr, Iowa City, IA 52242 USA

来源：

CLEVELAND CLINIC JOURNAL OF MEDICINE | 2004年 / 71卷 / 09期

关键词：

D O I：

10.3949/ccjm.71.9.729

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Elevated plasma homocysteine is associated with an increased risk of myocardial infarction, stroke, and venous thromboembolism. Folic acid and other B vitamins lower plasma homocysteine levels, but whether this therapy confers a clinical benefit has yet to be determined. Until we know the results of ongoing clinical trials of homocysteine-lowering therapy, testing for and treating elevated homocysteine is probably justified only in patients with known cardiovascular disease or who are at high risk.

引用

页码：729 / 734

页数：6

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