Antimicrobial activity of hydroxylbenzenesulfonailides derivatives of chitosan, chitosan sulfates and carboxymethyl chitosan

被引:73
作者
Zhong, Zhimei [1 ,2 ]
Li, Pengcheng [1 ]
Xing, Ronge [1 ]
Liu, Song [1 ]
机构
[1] Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China
[2] Inner Mongolia Agr Univ, Coll Sci, Hohhot 010018, Peoples R China
关键词
Hydroxylbenzenesulfonailides; Chitosan; Carboxymethyl chitosan; Chitosan sulfate; Antimicrobial activity; PULP; SALT;
D O I
10.1016/j.ijbiomac.2009.04.020
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
070307 [化学生物学]; 071010 [生物化学与分子生物学];
摘要
Chitosan, carboxymethyl chitosan (CIVICS) and chitosan sulfates (CSS) with different molecular weight were modified by reacting with 4-hydroxyl-5-chloride-1,3-benzene-disulfo-chloride or 2-hydroxyl-5-chloride-1,3 -benzene-disulfo-chloride to give 12 kinds of new hydroxylbenzenesulfonailides derivatives of them. The preparation conditions of the derivatives were discussed in this paper, and their structures were characterized by FT-IR and C-13 NMR spectroscopy. The solubility of the derivatives was measured in the experiment. In addition, their antimicrobial activities against four bacteria and five crop-threatening pathogenic fungi were tested in the experiment. Besides, the rule and mechanism of their antibacterial activities were discussed in this paper. (C) 2009 Published by Elsevier B.V.
引用
收藏
页码:163 / 168
页数:6
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