Transcription activation: Unveiling the essential nature of TFIID

被引：29

作者：

Chen, BS ^{[1
]}

Hampsey, M ^{[1
]}

机构：

[1] Robert Wood Johnson Med Sch, Dept Biochem, Div Nucl Acids Enzymol, Piscataway, NJ 08854 USA

来源：

CURRENT BIOLOGY | 2002年 / 12卷 / 18期

关键词：

D O I：

10.1016/S0960-9822(02)01134-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The TAF subunits of TFIID mediate activation of subsets of the eukaryotic genome. Recent results demonstrate that TFIID is recruited to promoters in an activator-specific manner involving functional interaction between upstream regulatory elements and the core promoter, thereby coordinating the expression of distinct sets of genes.

引用

页码：R620 / R622

页数：3

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