Chemical constituents of the aerial part of Celastrus hypoleucus

被引：17

作者：

Wang, H ^{[1
]}

Tian, X ^{[1
]}

Chen, YZ ^{[1
]}

机构：

[1] Lanzhou Univ, Natl Lab Appl Organ Chem, Lanzhou 730000, Peoples R China

来源：

JOURNAL OF THE CHINESE CHEMICAL SOCIETY | 2002年 / 49卷 / 03期

关键词：

Celastraceae; Celastrus hypoleucus; aerial part; antilipoperoxidative effect; free radicals; in vitro;

D O I：

10.1002/jccs.200200068

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Fourteen compounds including eight triterpenoids, 12-oleanaen-3beta-ol (beta-amyrin) (1), 12-oleanaen-3beta-caffeate (2), 9(11),12-oleanadien-3beta-ol (3), 9(11),12-oleanadien-3-one (4), 9(11),12-oleanadien-3beta-caffeate (5), friedela-3-one (friedelin) (6), friedela-3-one-29-ol (7), and 12-gammateraen-3beta-ol (tetrehymanol) (8); one steroid, beta-sitosterol (9); one long-chain acid, octadecadienoic acid (10); two esters, ester of n-octaolecyl-4-hydroxy-cinnamate (11), and ester of n-octadecyl-caffeic acid (12); one diterpene, 8beta,19-dihydroxy-3-oxopimar- 15-ene (13); one sesquiterpene, 1beta,2beta,9alpha-trihydroxy-beta-dihydroagarofuran (14) were isolated from the aerial part of Celastrus hypoleucus, These compounds were characterized and identified by physical and spectral methods. All compounds were isolated for the first time from this plant. Among them 12-oleanaen-3beta- caffeate (2) and 9(11),12-oleanadien-3beta-caffeate (5) are two new compounds, and ester of n-octadecyl-caffeic acid (12) possessed antilipoperoxidative effect by specifically scavenging the hydroxyl free radical (.OH) in vitro.

引用

页码：433 / 436

页数：4

共 19 条

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