Advancing Genetic Theory and Application by Metabolic Quantitative Trait Loci Analysis

被引：53

作者：

Kliebenstein, Daniel J. ^{[1
,2
]}

机构：

[1] Univ Calif Davis, Genet Grad Grp, Davis, CA 95616 USA

[2] Univ Calif Davis, Dept Plant Sci, Davis, CA 95616 USA

来源：

PLANT CELL | 2009年 / 21卷 / 06期

基金：

美国国家科学基金会;

关键词：

ALIPHATIC GLUCOSINOLATE BIOSYNTHESIS; ARABIDOPSIS-THALIANA; NATURAL VARIATION; FAILURE PROPAGATION; INSECT RESISTANCE; ENZYME-ACTIVITIES; EXPRESSION; EVOLUTION; IDENTIFICATION; DUPLICATION;

D O I：

10.1105/tpc.109.067611

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This review describes recent advances in the analysis of metabolism using quantitative genetics. It focuses on how recent metabolic quantitative trait loci (QTL) studies enhance our understanding of the genetic architecture underlying naturally variable phenotypes and the impact of this fundamental research on agriculture, specifically crop breeding. In particular, the role of whole-genome duplications in generating quantitative genetic variation within a species is highlighted and the potential uses of this phenomenon presented. Additionally, the review describes how new observations from metabolic QTL mapping analyses are helping to shape and expand the concepts of genetic epistasis.

引用

页码：1637 / 1646

页数：10

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