Lanthanide Lewis acid-mediated enantioselective conjugate radical additions

被引：37

作者：

Sibi, MP ^{[1
]}

Manyem, S ^{[1
]}

机构：

[1] N Dakota State Univ, Dept Chem, Fargo, ND 58105 USA

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 17期

关键词：

D O I：

10.1021/ol026327h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Lanthanide triflates along with proline-derived ligands have been found to be efficient catalysts for enantioselective conjugate addition of nucleophilic radicals to enoates. N-Acyl oxazolidinones, when used as achiral additives, gave meaningful enhancements in the ees for the product.

引用

页码：2929 / 2932

页数：4

共 55 条

[21]

Krause N, 2001, SYNTHESIS-STUTTGART, P171

[22]

Lacôte E, 1998, ANGEW CHEM INT EDIT, V37, P2259, DOI 10.1002/(SICI)1521-3773(19980904)37:16<2259::AID-ANIE2259>3.0.CO

[23]

2-U

[24]

Leonard J, 1998, EUR J ORG CHEM, V1998, P2051