Heterogeneously catalyzed selective N-alkylation of aromatic and heteroaromatic amines with alcohols by a supported ruthenium hydroxide

被引：140

作者：

Kim, Jung Won ^{[1
]}

Yamaguchi, Kazuya ^{[1
,2
]}

Mizuno, Noritaka ^{[1
,2
]}

机构：

[1] Univ Tokyo, Sch Engn, Dept Appl Chem, Bunkyo Ku, Tokyo 1138656, Japan

[2] Japan Sci & Technol Agcy JST, CREST, Kawaguchi, Saitama 3320012, Japan

来源：

JOURNAL OF CATALYSIS | 2009年 / 263卷 / 01期

基金：

日本科学技术振兴机构;

关键词：

Alcohols; Amines; Heterogeneous catalysis; N-alkylation; Ruthenium hydroxide; HYDROGEN-TRANSFER REACTIONS; RANEY NICKEL; ANILINE; OXIDATIONS; METHANOL; ALUMINA; SCOPE;

D O I：

10.1016/j.jcat.2009.01.020

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The N-alkylation of aromatic and heteroaromatic amines with alcohols could efficiently be promoted by an easily prepared supported ruthenium hydroxide catalyst Ru(OH)(x)/Al2O3. A variety of aromatic and heteroaromatic amines were selectively converted into the corresponding secondary amines in moderate to excellent yields without any co-catalysts such as bases and stabilizing ligands. The observed catalysis was intrinsically heterogeneous and the Ru(OH)(x)/Al2O3 catalyst recovered after the reaction could be reused without an appreciable loss of its high catalytic performance for the N-alkylation. (C) 2009 Elsevier Inc. All rights reserved.

引用

页码：205 / 208

页数：4

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