Primary pulmonary hypertension: Update on pathogenesis and novel therapies

被引：12

作者：

Arroliga, AC ^{[1
]}

Dweik, RA ^{[1
]}

Kaneko, FJT ^{[1
]}

Erzurum, SC ^{[1
]}

机构：

[1] Cleveland Clin Fdn, Med Intens Care Unit, Dept Pulm & Crit Care Med, Cleveland, OH 44195 USA

来源：

CLEVELAND CLINIC JOURNAL OF MEDICINE | 2000年 / 67卷 / 03期

关键词：

D O I：

10.3949/ccjm.67.3.175

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Primary pulmonary hypertension is a progressive and fatal disease that chiefly affects young adults. Although its etiology is a mystery, recent research has uncovered several biochemical derangements in this disorder, and new therapies are prolonging survival.

引用

页码：175 / +

页数：12

共 50 条

[1] Pulmonary hypertension: NO therapy? [J].

Adnot, S ;

Raffestin, B .

THORAX, 1996, 51 (07) :762-764

[2]

[Anonymous], 1998, Am J Respir Crit Care Med, V158, P335

[3] A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension [J].

Barst, RJ ;

Rubin, LJ ;

Long, WA ;

McGoon, MD ;

Rich, S ;

Badesch, DB ;

Groves, BM ;

Tapson, VF ;

Bourge, RC ;

Brundage, BH ;

Koerner, SK ;

Langleben, D ;

Keller, CA ;

Murali, S ;

Uretsky, BF ;

Clayton, LM ;

Jobsis, MM ;

Blackburn, SD ;

Shortino, D ;

Crow, JW .

NEW ENGLAND JOURNAL OF MEDICINE, 1996, 334 (05) :296-301

[4] Plasma levels of thrombomodulin in pulmonary hypertension [J].

Cacoub, P ;

Karmochkine, M ;

Dorent, R ;

Nataf, P ;

Piette, JC ;

Godeau, P ;

Gandjbakhch, I ;

Boffa, MC .

AMERICAN JOURNAL OF MEDICINE, 1996, 101 (02) :160-164

[5] Pulsed delivery of inhaled nitric oxide to patients with primary pulmonary hypertension - An ambulatory delivery system and initial clinical tests [J].

Channick, RN ;

Newhart, JW ;

Johnson, FW ;

Williams, PJ ;

Auger, WR ;

Fedullo, PF ;

Moser, KM .

CHEST, 1996, 109 (06) :1545-1549

[6] The role of thrombosis in severe pulmonary hypertension [J].

Chaouat, A ;

Weitzenblum, E ;

Higenbottam, T .

EUROPEAN RESPIRATORY JOURNAL, 1996, 9 (02) :356-363

[7] AN IMBALANCE BETWEEN THE EXCRETION OF THROMBOXANE AND PROSTACYCLIN METABOLITES IN PULMONARY-HYPERTENSION [J].

CHRISTMAN, BW ;

MCPHERSON, CD ;

NEWMAN, JH ;

KING, GA ;

BERNARD, GR ;

GROVES, BM ;

LOYD, JE .

NEW ENGLAND JOURNAL OF MEDICINE, 1992, 327 (02) :70-75

[8] Role of nitric oxide in the local regulation of pulmonary vascular resistance in humans [J].

Cooper, CJ ;

Landzberg, MJ ;

Anderson, TJ ;

Charbonneau, F ;

Creager, MA ;

Ganz, P ;

Selwyn, AP .

CIRCULATION, 1996, 93 (02) :266-271

[9] SURVIVAL IN PATIENTS WITH PRIMARY PULMONARY-HYPERTENSION - RESULTS FROM A NATIONAL PROSPECTIVE REGISTRY [J].

DALONZO, GE ;

BARST, RJ ;

AYRES, SM ;

BERGOFSKY, EH ;

BRUNDAGE, BH ;

DETRE, KM ;

FISHMAN, AP ;

GOLDRING, RM ;

GROVES, BM ;

KERNIS, JT ;

LEVY, PS ;

PIETRA, GG ;

REID, LM ;

REEVES, JT ;

RICH, S ;

VREIM, CE ;

WILLIAMS, GW ;

WU, M .

ANNALS OF INTERNAL MEDICINE, 1991, 115 (05) :343-349

[10] COANCESTRY IN APPARENTLY SPORADIC PRIMARY PULMONARY-HYPERTENSION [J].

ELLIOTT, G ;

ALEXANDER, G ;

LEPPERT, M ;

YEATES, S ;

KERBER, R .

CHEST, 1995, 108 (04) :973-977

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