Genetics of cardiac repolarization

被引：5

作者：

Shah, Svati H. ^{[1
]}

Pitt, Geoffrey S. ^{[1
]}

机构：

[1] Duke Univ, Med Ctr, Dept Med, Div Cardiol, Durham, NC 27710 USA

来源：

NATURE GENETICS | 2009年 / 41卷 / 04期

关键词：

LONG-QT SYNDROME; INTERVAL; MORTALITY; VARIANTS;

D O I：

10.1038/ng0409-388

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Prolongation of the electrocardiographic QT interval, a measure of cardiac repolarization, is associated with arrhythmogenic disorders and is a risk factor for sudden cardiac death. Two genome-wide association studies (GWAS) of variation in the QT interval in population-based cohorts now report association with variants in a subset of ion channel genes and other new associations.

引用

页码：388 / 389

页数：3

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