The physics behind the larger scale organization of DNA in eukaryotes

被引：61

作者：

Emanuel, Marc ^{[1
]}

Radja, Nima Hamedani ^{[1
]}

Henriksson, Andreas ^{[1
]}

Schiessel, Helmut ^{[1
]}

机构：

[1] Leiden Univ, Inst Lorentz Theoret Natuurkunde, NL-2300 RA Leiden, Netherlands

来源：

PHYSICAL BIOLOGY | 2009年 / 6卷 / 02期

关键词：

NUCLEOSOME CORE PARTICLES; HIGHER-ORDER STRUCTURE; CHROMATIN FIBER STRUCTURE; INTERPHASE CHROMOSOMES; MITOTIC CHROMOSOMES; LINKER HISTONE; TOPOISOMERASE-II; NUCLEUS; MODEL; DOMAINS;

D O I：

10.1088/1478-3975/6/2/025008

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In this paper, we discuss in detail the organization of chromatin during a cell cycle at several levels. We show that current experimental data on large-scale chromatin organization have not yet reached the level of precision to allow for detailed modeling. We speculate in some detail about the possible physics underlying the larger scale chromatin organization.

引用

页数：11

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