Real-time three-dimensional optoacoustic imaging using an acoustic lens system

被引:66
作者
Niederhauser, JJ [1 ]
Jaeger, M [1 ]
Frenz, M [1 ]
机构
[1] Univ Bern, Inst Appl Phys, CH-3012 Bern, Switzerland
关键词
D O I
10.1063/1.1777820
中图分类号
O59 [应用物理学];
学科分类号
摘要
In medical optoacoustics (photoacoustics), absorbing structures, such as blood vessels, hidden inside scattering media are illuminated with short laser pulses resulting in the generation of thermoelastic pressure transients. This initial three-dimensional (3D) acoustic pressure distribution, which exactly resembles the absorption distribution, was imaged into a water container with a 4f acoustic lens system. An optical dark-field stereo imaging system using a 30 ns flash illumination light was used to capture a snapshot of the pressure-induced refraction index changes in the water container at a predetermined time after the original laser pulse. The imaging system works at 20 Hz frame rate and was designed toward a theoretical resolution of 50 mum. The proposed method directly provides 3D images of absorbing structures without the need of computational reconstruction algorithms. (C) 2004 American Institute of Physics.
引用
收藏
页码:846 / 848
页数:3
相关论文
共 14 条
[1]   Detection of ultrawide-band ultrasound pulses in optoacoustic tomography [J].
Andreev, VG ;
Karabutov, AA ;
Oraevsky, AA .
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 2003, 50 (10) :1383-1390
[2]   Extrinsic optical-fiber ultrasound sensor using a thin polymer film as a low-finesse Fabry-Perot interferometer [J].
Beard, PC ;
Mills, TN .
APPLIED OPTICS, 1996, 35 (04) :663-675
[3]   ULTRASONIC-IMAGING WITH AN ACOUSTIC LENS [J].
BEAVER, WL ;
DAMERON, DH ;
MACOVSKI, A .
IEEE TRANSACTIONS ON SONICS AND ULTRASONICS, 1977, 24 (04) :235-243
[4]  
BERGMANN L, 1949, ULTRASCHALL ANWENDUN
[5]   Laser-generated cavitation in absorbing liquid induced by acoustic diffraction [J].
Frenz, M ;
Paltauf, G ;
SchmidtKloiber, H .
PHYSICAL REVIEW LETTERS, 1996, 76 (19) :3546-3549
[6]   Image reconstruction for photoacoustic scanning of tissue structures [J].
Hoelen, CGA ;
de Mul, FFM .
APPLIED OPTICS, 2000, 39 (31) :5872-5883
[7]   In vivo photoacoustic imaging of blood vessels using an extreme-narrow aperture sensor [J].
Kolkman, RGM ;
Hondebrink, E ;
Steenbergen, W ;
de Mul, FFM .
IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS, 2003, 9 (02) :343-346
[8]   Optoacoustic imaging using a three-dimensional reconstruction algorithm [J].
Köstli, KP ;
Frauchiger, D ;
Niederhauser, JJ ;
Paltauf, G ;
Weber, HP ;
Frenz, M .
IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS, 2001, 7 (06) :918-923
[9]   PHOTOACOUSTIC ULTRASOUND (PAUS) - RECONSTRUCTION TOMOGRAPHY [J].
KRUGER, RA ;
LIU, PY ;
FANG, YR ;
APPLEDORN, CR .
MEDICAL PHYSICS, 1995, 22 (10) :1605-1609
[10]   Comparison of laser-induced and classical ultrasound [J].
Niederhauser, JJ ;
Jaeger, M ;
Frenz, M .
BIOMEDICAL OPTOACOUSTICS IV, 2003, 4960 :118-123