HLA in Egyptian children with biliary atresia

被引：15

作者：

A-Kader, HH

El-Ayyouti, M

Hawas, S

Abdalla, A

Al-Tonbary, Y

Bassiouny, M

Boneberg, A

El-Sallab, S

机构：

[1] Upstate Med Univ, Dept Pediat, Div Gastroenterol & Nutr, Syracuse, NY 13210 USA

[2] Mansoura Univ, Childrens Hosp, Dept Pediat, Mansoura, Egypt

[3] Mansoura Univ, Childrens Hosp, Dept Immunol, Mansoura, Egypt

[4] Mansoura Univ, Childrens Hosp, Dept Microbiol, Mansoura, Egypt

来源：

JOURNAL OF PEDIATRICS | 2002年 / 141卷 / 03期

关键词：

D O I：

10.1067/mpd.2002.127506

中图分类号：

R72 [儿科学];

学科分类号：

100202 [儿科学];

摘要：

We studied the human leukocytes antigens in 18 Egyptian children with biliary atresia (BA) without extrahepatic congenital malformations. There was a significant increased frequency of both B8 and DR3 (83.3% and 94.4% in patients with BA compared with 6.5% and 14.9% in the general population, respectively). Ten patients had the B8/DR3 haplotype. Our results support the hypothesis that genetic factors may play a role in susceptibility to BA.

引用

页码：432 / 434

页数：3

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[2]

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[3]

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[4]

BODMER WF, 1978, HISTOCOMPATIBILITY T, P22