Palladium-Catalyzed Direct Arylation of Electron-Deficient Polyfluoroarenes with Arylboronic Acids

被引：117

作者：

Wei, Ye ^{[1
]}

Kan, Jian ^{[1
]}

Wang, Min ^{[1
]}

Su, Weiping ^{[1
]}

Hong, Maochun ^{[1
]}

机构：

[1] Chinese Acad Sci, Fujian Inst Res Struct Matter, State Key Lab Struct Chem, Fuzhou 350002, Fujian, Peoples R China

来源：

ORGANIC LETTERS | 2009年 / 11卷 / 15期

关键词：

H BOND FUNCTIONALIZATION; CROSS-COUPLING REACTIONS; AROMATIC KETONES; ROOM-TEMPERATURE; N-OXIDES; INDOLES; (HETERO)ARENES; ALKENYLATION; OLEFINATION; ACTIVATION;

D O I：

10.1021/ol901200g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The palladium-catalyzed direct arylation of electron-deficient arenes that contain two or more fluorine groups with arylboronic acids was realized. The key to achieving a broad substrate scope with respect to both polyfluorobenzenes and arylboronic acids is the choice of bases depending on acidities of polyfluorobenzenes.

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页码：3346 / 3349

页数：4

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