Telomerase: A target for cancer therapeutics

被引：273

作者：

Shay, JW ^{[1
]}

Wright, WE ^{[1
]}

机构：

[1] Univ Texas, SW Med Ctr, Dallas, TX 75309 USA

来源：

CANCER CELL | 2002年 / 2卷 / 04期

关键词：

D O I：

10.1016/S1535-6108(02)00159-9

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The continuous growth of advanced malignancies almost universally correlates with the reactivation of telomerase. While there is still a great deal of basic and applied research to be done, telomerase remains a very attractive novel target for cancer therapeutics. In this review, we will discuss the challenges and the pros and cons of the most promising antitelomerase approaches currently being investigated. Copyright © 2002 Cell Press.

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收藏

页码：257 / 265

页数：9

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