A concise asymmetric route to the bridged bicyclic tropane alkaloid ferruginine using enyne ring-closing metathesis

被引：69

作者：

Aggarwal, VK ^{[1
]}

Astle, CJ ^{[1
]}

Rogers-Evans, M ^{[1
]}

机构：

[1] Univ Bristol, Sch Chem, Bristol BS8 1TS, Avon, England

来源：

ORGANIC LETTERS | 2004年 / 6卷 / 09期

关键词：

D O I：

10.1021/ol049665m

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Enyne metathesis has been used to prepare bridged azabicycles and applied in a short asymmetric synthesis of the tropane ferruginine. A Grubbs first generation catalyst proved to be superior to the second generation catalyst in the enyne metathesis reaction.

引用

页码：1469 / 1471

页数：3

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