Rhodium(I)-catalyzed [2+2+2] cycloadditions of ynamides in the synthesis of amide-substituted chiral biaryls

被引：41

作者：

Tracey, Michael R.

Oppenheimer, Jossian

Hsung, Richard P.

机构：

[1] Univ Wisconsin, Div Pharmaceut Sci, Madison, WI 53705 USA

[2] Univ Wisconsin, Dept Chem, Madison, WI 53705 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2006年 / 71卷 / 22期

关键词：

D O I：

10.1021/jo061683p

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Rhodium(I)-catalyzed [2 + 2 + 2] cycloadditions of sterically encumbered aryl-substituted ynamides with various diynes are described here. These cycloadditions provide the synthesis of an array of new chiral amide-substituted biaryls that can be useful in future chiral ligand designs.

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页码：8629 / 8632

页数：4

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