Platelet glycoprotein IIb/IIIa inhibitors - Basic and clinical aspects

被引:51
作者
Nurden, AT [1 ]
Poujol, C
Durrieu-Jais, C
Nurden, P
机构
[1] Hop Cardiol, CNRS, UMR 5533, F-33604 Pessac, France
[2] Hop Cardiol, Inst Federatif Rech Coeur Vaisseaux Thrombose, Unite Soins Intensifs, F-33604 Pessac, France
关键词
glycoproteins; abciximab; platelet aggregation; antithrombotic drugs;
D O I
10.1161/01.ATV.19.12.2835
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:2835 / 2840
页数:6
相关论文
共 41 条
[11]  
Hanrath P, 1997, CIRCULATION, V96, P1445
[12]   Inhibition of platelet-mediated clot retraction by integrin antagonists [J].
Hantgan, RR ;
Mousa, SA .
THROMBOSIS RESEARCH, 1998, 89 (06) :271-279
[13]   Pharmacodynamic efficacy, clinical safety, and outcomes after prolonged platelet glycoprotein IIb/IIIa receptor blockade with oral xemilofiban - Results of a multicenter, placebo-controlled, randomized trial [J].
Kereiakes, DJ ;
Kleiman, NS ;
Ferguson, JJ ;
Masud, Z ;
Broderick, TM ;
Abbottsmith, CW ;
Runyon, JP ;
Anderson, LC ;
Anders, RJ ;
Dreiling, RJ ;
Hantsbarger, GL ;
Bryzinski, B ;
Topol, EJ .
CIRCULATION, 1998, 98 (13) :1268-1278
[14]   DIFFERENTIAL INHIBITION OF PLATELET-AGGREGATION INDUCED BY ADENOSINE-DIPHOSPHATE OR A THROMBIN RECEPTOR-ACTIVATING PEPTIDE IN PATIENTS TREATED WITH BOLUS CHIMERIC 7E3 FAB - IMPLICATIONS FOR INHIBITION OF THE INTERNAL POOL OF GPIIB/IIIA RECEPTORS [J].
KLEIMAN, NS ;
RAIZNER, AE ;
JORDAN, R ;
WANG, AL ;
NORTON, D ;
MACE, KF ;
JOSHI, A ;
COLLER, BS ;
WEISMAN, HF .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1995, 26 (07) :1665-1671
[15]   Increased platelet responsiveness following coronary stenting - Heparin as a possible aetiological factor in stent thrombosis [J].
Knight, CJ ;
Panesar, M ;
Wilson, DJ ;
Patrineli, A ;
Chronos, N ;
Wright, C ;
Clarke, D ;
Patel, D ;
Fox, K ;
Goodall, AH .
EUROPEAN HEART JOURNAL, 1998, 19 (08) :1239-1248
[16]   Pharmacodynamic profile of short-term abciximab treatment demonstrates prolonged platelet inhibition with gradual recovery from GP IIb/IIIa receptor blockade [J].
Mascelli, MA ;
Lance, ET ;
Damaraju, L ;
Wagner, CL ;
Weisman, HF ;
Jordan, RE .
CIRCULATION, 1998, 97 (17) :1680-1688
[17]   Oral antiplatelet efficacy and specificity of a novel nonpeptide platelet GPIIb/IIIa receptor antagonist, DMP 802 [J].
Mousa, SA ;
Olson, RE ;
Bozarth, JM ;
Lorelli, W ;
Forsythe, MS ;
Racanelli, A ;
Gibbs, S ;
Schlingman, K ;
Bozarth, T ;
Kapil, R ;
Wityak, J ;
Sielecki, TM ;
Wexler, RR ;
Thoolen, MJ ;
Slee, A ;
Reilly, TM ;
Anderson, PS ;
Friedman, PA .
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1998, 32 (02) :169-176
[18]   ''Rescue'' utilization of abciximab for the dissolution of coronary thrombus developing as a complication of coronary angioplasty [J].
Muhlestein, JB ;
Karagounis, LA ;
Treehan, S ;
Anderson, JL .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1997, 30 (07) :1729-1734
[19]   Distribution of ligand-occupied alpha(IIb)beta(3) in resting and activated human platelets determined by expression of a novel class of ligand-induced binding site recognized by monoclonal antibody AP6 [J].
Nurden, P ;
Humbert, M ;
Piotrowicz, RS ;
Bihour, C ;
Poujol, C ;
Nurden, AT ;
Kunicki, TJ .
BLOOD, 1996, 88 (03) :887-899
[20]  
Nurden P, 1997, THROMB HAEMOSTASIS, V78, P1305