Cancer - p53 sends nucleotides to repair DNA

被引：105

作者：

Lozano, G ^{[1
]}

Elledge, SJ

机构：

[1] Univ Texas, MD Anderson Canc Ctr, Dept Mol Genet, Houston, TX 77030 USA

[2] Baylor Coll Med, Dept Biochem & Mol Biol, Houston, TX 77030 USA

来源：

NATURE | 2000年 / 404卷 / 6773期

关键词：

D O I：

10.1038/35003670

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Mutations in the p53 protein or components of the pathway that regulates it are one of the main causes of cancer – normally, p53 prevents cells that have been damaged from contributing to tumour formation. Now another function of p53 emerges. It seems that the protein also participates in the process of DNA repair itself.

引用

页码：24 / 25

页数：2